Alzheimer's Disease Drug Trials To Start

Humanetics Corporation and Mount Sinai School of Medicine to Begin Clinical Trials of New Alzheimer's Compound; FDA Clears the Way with Approval of Investigational New Drug (IND) Application

 

MINNEAPOLIS--(BUSINESS WIRE)--March 30, 2006--In an announcement today, Humanetics Corporation said that the Food & Drug Administration (FDA) has approved the start of human trials for Humanetics' promising new oral compound, NIC5-15, aimed at combating Alzheimer's disease.

 

Based on the Investigational New Drug Application (IND) submitted to FDA for NIC5-15, Mount Sinai School of Medicine (MSSM) will proceed immediately with Phase I and Phase II studies in a population of early stage Alzheimer's disease patients. The studies will be conducted at Mount Sinai in New York and at the Bronx VA Medical Center. According to Giulio Maria Pasinetti, M.D., Ph.D. of Mount Sinai's Department of Psychiatry and the clinical trials' principal investigator, "the studies will measure safety, dosing, efficacy and biomarkers for Alzheimer's disease."

 

"We are pleased that FDA has approved the start of clinical trials for NIC5-15," stated Ronald Zenk, President and CEO of Humanetics. "NIC5-15 represents the potential for a new class of compounds focused on modifying the disease itself by slowing or preventing its progression," he said.

 

Humanetics and Mount Sinai School of Medicine Working Collaboratively

 

In December 2005, Humanetics entered into two agreements with Mount Sinai School of Medicine connected to the development of NIC5-15. The first is a clinical research agreement related to this announcement, which allows investigators at Mount Sinai to study Alzheimer's patients to assess if NIC5-15 is well tolerated and to compare doses with respect to tolerability and clinical efficacy. The second--an exclusive licensing agreement--provides Humanetics with exclusive rights under pending patents to commercialize products containing NIC5-15.

 

In the earlier pre-clinical studies and animal models, NIC5-15 was found to be effective in preventing the formation or slowing the progression of beta amyloid plaques, which are believed to be a cause of Alzheimer's disease. In animal models specifically, moderate doses of the compound improved cognitive function in mice with Alzheimer's type neuropathology and memory impairment.

 

Discovery and development of NIC5-15 for Alzheimer's disease has been under the direction of Dr. Pasinetti who added that "NIC5-15 was chosen to move into human trials because of its selectivity, safety and potency--making it an ideal agent for long-term prophylactic administration in this population."

 

About Mount Sinai School of Medicine
Located in Manhattan, Mount Sinai School of Medicine is internationally recognized for ground-breaking clinical and basic-science research, and innovative approaches to medical education. Through the Mount Sinai Graduate School of Biological Sciences, Mount Sinai trains biomedical researchers with an emphasis on the rapid translation of discoveries of basic research into new techniques for fighting disease. One indication of Mount Sinai's leadership in scientific investigation is its receipt during fiscal year 2004 of $153.2 million. Mount Sinai now ranks 25th among the nation's medical schools in receipt of research support from NIH. Mount Sinai School of Medicine also is known for unique educational programs such as the Humanities in Medicine program, which creates opportunities for liberal arts students to pursue medical school, and instructional innovations like The Morchand Center, the nation's largest program teaching students and physicians with "standardized patients" to become not only highly skilled, but compassionate caregivers. Long dedicated to improving its community, the School extends its boundaries to work with East Harlem and surrounding communities to provide access to health care and educational programs to at risk populations.

 

About Humanetics Corporation
Humanetics is a privately-held specialty pharmaceutical company headquartered in Minneapolis, Minnesota. The Company is focused on the rapid discovery, development and commercialization of orally-administered bioactive compounds for prevention and treatment of diseases in categories with urgent and unmet needs. The Company has several proprietary compounds in preclinical and/or clinical stages of development in the areas of Alzheimer's disease, bioterrorism and obesity. For further information, visit: http://www.humaneticscorp.com.

 

This Press Release contains discussion of certain expectations regarding Humanetics' future performance. These forward-looking statements are based on the Company's current views and assumptions. Actual results could differ materially from these current expectations and projections, and from historical performance.

 

Contacts
Latitude
Pam Pettinella, 952-404-1853
pam@latitude-c.com

Anti-Counterfeiting Label Catches Eye, Counterfeit Products

3M Introduces New Confirm Security Label with Floating Image Technology at Authentication Connections Forum in Tampa, Fla.; Strong Overt and Covert Technologies Combine to Help Fight Counterfeit Products

 

ST. PAUL, Minn.--(BUSINESS WIRE)--March 28, 2006--3M today announced its newest, high-security anti-counterfeiting label will be introduced on March 30 at the Authentication Connections Forum in Tampa, Fla. This new security solution, the 3M Confirm authentication label with floating image technology, incorporates a unique eye-visible security feature that provides powerful product authentication and can be verified easily with or without the use of a tool.

 

The label's floating image has an optically variable device (OVD) - a unique, overt security feature. The OVD image appears to "float" above or "sink" below the surface of the label and then disappear as the viewing angle changes. Dramatic movement of the image is easy to detect and recognize using only the human eye, enabling quick and easy authentication that proves the label and product are genuine. The label also incorporates a very secure and time-tested covert security feature inherent to Confirm security material.

 

"Electronics, pharmaceuticals, automotive parts, apparel, and cosmetics - the list of items that are counterfeited is endless," said Bill Markovitz, marketing development manager, 3M Security Systems. "The new Confirm security label will allow manufacturers and distributors to certify their products as authentic and then let wholesalers, retailers and end-consumers rapidly identify fakes. 3M currently sells a similar security product to governments for passports and driver's license programs. That same high level of security now will be available for commercial applications."

 

These labels build on 3M's proven retroreflective security technology - 3M Confirm security labels - which have been very well-accepted in the security marketplace for more than 25 years. The new floating image security feature enhances the inherent security of Confirm authentication labels and is based on proprietary technology. Verification is easier than ever and can be accomplished by a diverse population.

 

For more than 30 years, 3M has provided premier security solutions and services that identify, authenticate, secure and track materials and information by combining security and productivity. Drawing on its broad technology base and expertise, 3M creates solutions for a wide array of security needs. Examples include issuance and authentication of travel documents and personal identification cards, brand and asset protection solutions to fight counterfeiting and tampering, file tracking solutions, and library security and workflow management solutions.

 

About 3M -- A Global, Diversified Technology Company
Every day, 3M people find new ways to make amazing things happen. Wherever they are, whatever they do, the company's customers know they can rely on 3M to help make their lives better. 3M's brands include Scotch, Post-it, Scotchgard, Thinsulate, Scotch-Brite, Filtrete, Command and Vikuiti. Serving customers in more than 200 countries around the world, the company's 69,000 people use their expertise, technologies and global strength to lead in major markets including consumer and office; display and graphics; electronics and telecommunications; safety, security and protection services; health care; industrial and transportation. For more information, including the latest product and technology news, visit www.3M.com.

 

3M, Confirm, Scotch, Post-it, Scotchgard, Thinsulate, Scotch-Brite, Filtrete, Command and Vikuiti are trademarks of 3M.

 

Contacts
3M Security Systems, St. Paul
Joan M. Olseen, 651-736-1163
or
3M Public Relations
Connie S. Thompson, 651-733-8914
http://www.3m.com/PressContact

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Bunkers Better: Concrete Homes Deemed Safe

Storm Resistant Homes Featured in First Ever State-Wide Concrete Home Open House Event Sponsored by the Aggregate and Ready Mix Association of Minnesota

BURNSVILLE, Minn.--(BUSINESS WIRE)--March 28, 2006--This spring, during Severe Weather Awareness Week, people will have the opportunity to visit over 70 storm resistant homes and commercial buildings featured in the first ever Minnesota State-Wide Concrete Home Open House. This open house event is being sponsored by the Aggregate and Ready Mix Association of Minnesota (ARM). The goal of the open house is to provide greater awareness of the safety provided by concrete homes constructed with insulated concrete forms (ICFs).

 

Homes built with ICF technology are highly resistant to severe weather and provide homeowners and businesses a safe place during tornados, hurricanes and high winds. ICF walls are built with foam insulation forms into which concrete is poured. Structures built with ICF technology are able to withstand severe storms and storm damage much better than conventionally framed walls. Debris driven by high winds presents the greatest hazard to homeowners and their homes during tornados. Laboratory testing at the Wind Engineering Research Center, Texas Tech University, compared the impact resistance of residential concrete wall construction to conventionally framed walls. The frame walls failed to stop the penetration of airborne hazards. The concrete walls successfully demonstrated the strength and mass to resist the impact of 100 mph wind driven debris.

 

Besides providing a very safe environment, ICF homes are also highly energy efficient and environmentally friendly.

 

The Minnesota State-Wide Concrete Homes Open House will feature completed homes, homes under construction and commercial buildings throughout Minnesota the weekend of April 22-23, 2006 which coincides with Severe Weather Awareness Week. Additional information about the event, including locations of featured homes and listings of ICF builders/installers in Minnesota, go to www.chooseconcretehomes.com or call ARM at 1-888-REDI-MIX.

 

Founded in 1950 as a state-wide, non-profit organization, the Aggregate & Ready Mix Association of Minnesota (ARM) is committed to supporting the aggregate and ready mix industries through promotion, education and advocacy in environmental and government issues.

 

Contacts
Aggregate & Ready Mix Association of Minnesota
Margaret Mills, 952-707-1250
mmills@armofmn.com

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Waiting Room Patients Targeted In Sick Scheme

VISI Networks Teams with LabCorp(R) to Launch LabCorp Health Network; A Direct-to-Patient Digital Signage Network for LabCorp's Patient Service Centers Nationwide
 
LabCorp Health Network (LHN) - a direct-to-patient digital signage network for LabCorp's Patient Service Centers - is a customized channel of healthcare information specifically designed to provide patients using LabCorp's patient service centers a comfortable waiting environment through the delivery of quality commercial, educational, informational and entertainment segments via an internet driven, nationally networked narrowcast system. (Photo: Business Wire)

 

ORLANDO, Fla.--(BUSINESS WIRE)--March 28, 2006--VISI Networks and Laboratory Corporation of America(R) Holdings (LabCorp(R)) (NYSE:LH), a leading, national provider of diagnostic services and a pioneer in new diagnostic technologies, have teamed to create the LabCorp Health Network - a direct-to-patient digital signage network for LabCorp's Patient Service Centers.

 

The LabCorp Health Network (LHN) is a customized channel of healthcare information specifically designed to provide patients using LabCorp's patient service centers a comfortable waiting environment through the delivery of quality commercial, educational, informational and entertainment segments via an internet driven, nationally networked narrowcast system. Presented on large, flat-panel screens installed in LabCorp's Patient Service Centers, LHN provides an opportunity for advertisers and content partners to reach a health conscious audience with known demographic and statistical data.

 

"Through the LabCorp Health Network, we are providing a dynamic channel to educate patients and visitors as to the latest testing procedures and preventive measures they can take to lead happier and healthier lives," said Joseph Erhart, CEO of VISI Networks.

 

"We are extremely excited about this network. This private channel represents an opportunity for LabCorp and their content partners to reach a sizeable health conscious audience with relevant messaging that connects directly with their customer base in a way that was previously impossible," said Michael Erhart, VP of Business Development for VISI Networks. "By being able to deliver messages directly to real patients - ensuring they receive the most up-to-date information in a timely manner - this narrowcast network establishes itself as a superior alternative to traditional media."

 

Currently, the LabCorp Health Network can be found in over 300 of LabCorp's more than 1,300 Patient Service Centers in the U.S.

 

About VISI Networks

 

Founded by nationally recognized wayfinding and signage information display system expert Joseph Erhart, VISI Networks develops proprietary network information display systems capable of delivering high-impact digital multimedia messages to targeted consumers. VISI Networks has tested their infrastructure with networks in Florida Hospital Critical Care Centers, SunTrust Bank and Orlando-Sanford International Airport. To learn more about VISI Networks, visit www.VISInetworks.com.

 

About LabCorp(R)

 

Laboratory Corporation of America(R) Holdings, a S&P 500 company with an investment-grade credit rating, is a pioneer in commercializing new diagnostic technologies and the first in its industry to embrace genomic testing. With annual revenues of $3.3 billion in 2005, approximately 24,000 employees nationwide, and more than 220,000 clients, LabCorp offers clinical assays ranging from routine blood analyses to HIV and genomic testing. LabCorp combines its expertise in innovative clinical testing technology with its Centers of Excellence: The Center for Molecular Biology and Pathology, in Research Triangle Park, NC; National Genetics Institute, Inc. in Los Angeles, CA; ViroMed Laboratories, Inc. based in Minneapolis, MN; The Center for Esoteric Testing in Burlington, NC; DIANON Systems, Inc. based in Stratford, CT, US LABS based in Irvine, CA, and Esoterix and its Colorado Coagulation, Endocrine Sciences, and Cytometry Associates laboratories. LabCorp clients include physicians, government agencies, managed care organizations, hospitals, clinical labs, and pharmaceutical companies. To learn more about LabCorp, visit www.LabCorp.com.

 

Contacts
Media Contacts
Tier 1 Public Relations
Dan Dyer, 513-478-7818
ddyer@tier1pr.com
or
LabCorp
Pam Sherry, 336-436-4855
sherryp@labcorp.com
OR
Advertising Contact
VISI Networks Inc.
Jenny Sue Rhoades, 407-566-1437
jennysue@visinetworks.comAt A Glance
VISI Networks
Source: via Business Wire
Updated  03/24/2006  by company 

---

[Editor's comments: Great. Now when I have to see a doctor I can look forward to having my desperate-for-a-distraction mind feed commercial messages not unlike waiting for a plane at the airport. I predict the day is near when you use a public restroom and close the door you will sit (or stand) to have a yammering screen that wants to take your moment of privacy and join you for a little marketing one-on-one.

 

It's information.  It's advertising.  It's intrusive.  And It's obnoxious.

 

(hris ]

Republican Domain Re-direction Looks Stupid, Petty

I just got a message that someone had posted on a forum:

 

This fall's US Senate campaign in the state of Tennessee will likely be between Republican Ed Bryant and Democrat Harold Ford Jr. Both are currently in the US House of Representatives.

I just read that Bryant's campaign registered the domain name www.FordforSenate.com. If you type that in you go to the Bryant campaign web site.

If you're so inclined to complain, here's Bryant's contact info:

Ed Bryant for Senate
5214 Maryland Way Suite 304
Brentwood, TN 37027
Phone: 615-373-2327
Fax: 615-373-9851
Email: info@edbryantforsenate.com

 

Leave it to a politician to make themselves look stupid. Do they think that someone looking for Ford will then be interested in Bryant? Do they think this will sway voters? I think the petty meanness of this action WILL help to sway voters, but not as intended.

(hris

Doyenne of White House News Correspondents, With Cojones!

Summary of Grindstaff Chronicles for March 24th, 2006

The important question the country needs Bush to answer is why he had decided to invade Iraq even before moving into the White House. A valiant reporter asked that very question of Bush on Tuesday’s White House press briefing.

When Helen Thomas showed the courage her colleagues lacked in spades and asked Bush this question, he turned into a spitting viper in an instant, and needless to say, did not answer.

Helen Thomas needs us all to hound this pathetic White House with her question, until it’s answered. We shouldn’t let the media fail to keep her question in the forefront. We deserve answers, even if they have to be obtained by harassment, censure, or impeachment.

Keywords

Helen Thomas, White House press corps, Absolut vodka, Rose’s Lime Juice, Downing Street Memos, PBS’ News Hour, The New York Times, Schramsberg Blanc de Noirs, La Ina Sherry, Viking grills, Volnay, Loire Valley Saumur-Champigny, censure, impeachment

©Copyright 2006 Grindstaff Chronicles. All Rights Reserved.
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It is intended to share the thoughts and lifestyle of people
who work hard, like to relax and enjoy life, and are often
dismayed by news, politics, and the events of the day
that defy common sense.
http://www.GrindstaffChronicles.com
================================================

Pundits Poo-Poo Google Print, Possibly Prematurely

Whoa, it seems that Google's first attempt to enter the print advertising world was not a hit right from the start.

 

http://www.searchengineguide.com/searchbrief/senews/007136.html

http://www.marketingpilgrim.com/2006/03/not-all-google-touches-turns-to-gold.html

http://www.businessweek.com/technology/content/mar2006/tc20060324_251660.htm

 

My, how quickly we are to condemn a first effort...! I was just reading an article today in 2/7/06 DM News about this and realized the vast potential of what Google is trying to do.

 

They should have purchased ad space in the same style as their on-line ads and put that up for bid right into AdWords. Small, deftly-worded ads that move from the online world to the off-line world complete with the Google brand. Once they make this kind of adjustment and stop trying to fit into the existing format they will have another winner, IMO.

 

It would be SO AWESOME to have our AdWords ads start to appear in newspapers and magazines like they do now on the content networks, and aside from the additional exposure, there's NO CLICK FRAUD! Plus we get to reach all those people that don't mind killing trees to get their daily fix of news.

 

I webmaster for a small Minnesota newspaper, The Watchdog News (http://www.watchdog-news.com) and I am going to suggest to the editor that we adopt the same type of ad format with content-related ads that you see from Google and other providers. Don't tell me I'm the only one that sees the potential here and the slap-your-head, simplicity of the concept...?

 

Hey, I dusted off the crystal ball, and guess what I just saw? HDTV sets in just about every home. No surprise there, but what DID take my breath away was seeing some content on those beautiful screens along one site of the screen and it looked to me to be damn 160x600 skyscraper ads!!! I couldn't make out if it was Gooooogle or Yahooooo! but I would lay some money on which one it will turn out to be... :-)

 

(hris

70-Year-Old Awarded $659,000 in St. Paul Defamation Suit

Jury Awards 70-Year-Old Tuan Pham $659,000 in Defamation Suit Closely Watched Nationally; Former South Vietnamese War Prisoner and St. Paul Community Leader Lost His Business and Honor over Baseless Charges

ST. PAUL, Minn.--(BUSINESS WIRE)--March 23, 2006--A former South Vietnamese soldier who was imprisoned for more than two years after the Vietnam War (primarily for supporting the Catholic Church) and who was later appointed by President George W. Bush to St. Paul's Vietnamese Educational Foundation (VEF), won a $659,000 defamation case against seven defendants whom the jury unanimously agreed ruined his business and his reputation. Tuan J. Pham, 70 years-old, his wife Mai Vu and their University Avenue grocery, Capital Market, won the verdict Wednesday, March 22, 2006, in a rancorous controversy that divided the Twin Cities Vietnamese community and was hotly debated nationally on Vietnamese radio programs.

According to the Plaintiff's Statement of the Case's Claims and Defenses in Ramsey County Second Judicial District Court, the lawsuit arose from events that were triggered by a visit to St. Paul by a Catholic Bishop from Vietnam on December 17, 2003. During his visit to Minnesota, the Bishop was escorted by Pham, a devout Catholic, who served as the Bishop's driver as he visited various members of the Catholic and Vietnamese communities in St. Paul.

Falsehoods spread over South Vietnam Flag incident with visiting Vietnam Catholic Bishop

En route to a meeting of Vietnamese community members at the Vietnam Center in St. Paul, the Bishop noted the presence of the flag of the former Republic of Vietnam flag flying over the center. The Bishop told Pham that he wanted to be taken to a private residence because he was under orders from the Catholic Church to avoid political situations during his visit to the United States that could lead to trouble for the Catholic Church with the Communist government in Vietnam. Pham entered the Vietnam Center and informed the Executive Director of the Bishop's concern about the flag. A decision was made to lower the flag momentarily for the Bishop's visit. After the meeting, the flag was again momentarily lowered while the Bishop exited the building and raised it again after his departure.

Defendants and others begin labeling South Vietnamese patriot a Communist

Subsequently a number of the defendants in this matter learned of the fact that the flag had been lowered to permit the Bishop to enter the Vietnam Center. Beginning in December 2003, a number of people in the Vietnamese community raised concerns about the Republic flag being lowered for the Bishop and called for the removal of the leadership of the organization that controls the Vietnam Center. They also claimed "moral turpitude" on the part of Pham and called for his removal from the Vietnamese Educational Foundation. Defendants, including Dean Do, who had at one time married one of Pham's daughters and used the marriage and the daughter's mental illness, allegedly to extort money from Pham and Capital Market, began labeling Pham a communist and mounted a slanderous personal campaign against him.

"I feel relieved this matter is resolved after two years of suffering for me and my family. As an American, I have always believed in the laws of this country, and I had faith that the court would protect our rights," says Pham. "It is wrong to hurt people or ruin their business with false claims. My family has suffered severely because of these baseless attacks. We brought this case for our children and their children to help the Vietnamese community work within the American system. Our young people must know that you must respect other's right and that you can fight for your dignity and honor and the law will back you." Pham says if he collects the awarded damages he hopes to build two Buddhist schools and one Catholic school in his native land.

Immigrant communities put on notice

"Tuan Pham's landmark case will change the way the Vietnamese and other immigrant communities operate as they gain full access an acceptance in the general community. The public debate must be free and robust, however, this verdict sends the message that slander and character assassination will not be tolerated under our laws," says Pham's attorney Darrin Rosha of Scherzo and Trio Legal Advisors, PLLC in St. Paul. "Mr. Pham, his family, and his business clearly suffered at the hands of the defendants in this case. They not only spread false and malicious statements about him, including false claims of criminal acts, but also forced a community boycott of his grocery business and brought it to ruin. The jury wisely and unanimously upheld his rights as an American citizen to redress those wrongs."

For more information - or to interview Tuan Pham or Darrin Rosha - please contact Martin Keller at Media Savant Communications Co., 612-729-8585 or mkeller@mediasavant.com

Contacts

Media Savant Communications Co.
Martin Keller, 612-729-8585
mkeller@mediasavantcom.com

New Article-Free Fashion Magazine Launched

Cashak Magazine Launches Preview of New Fashion Publication
 
Press Release by: Cashak Magazine 

 

(openPR) - Two years after losing his web advertising business to a crooked partner and six months after leaving his photographer position at a deteriorating periodical, Christopher Cashak launches a world-wide online preview of his new publication- Cashak Magazine. Christopher Cashak, a veteran of the media and technology fields, brings the fashion industry an original magazine which embraces new thinking and ideas. Cashak Magazine is the first to be filmed entirely on location in wide-screen format. The magazine has no articles, but brings its audience fashion and beauty advice through direct interviews. By producing all of its material Cashak Magazine sets a new standard in publishing. Cashak Magazine focuses on the sexy styles and trends that affluent, fashion minded women wear. The preview, now online at http://www.cashakmagazine.com/ , brings the world a taste of Christopher Cashak's new publication.

 

Many have heard Christopher Cashak's core philosophy that: "Fashion is meant to be seen, not read about in articles." Cashak Magazine primarily tells fashion's story through pictures. The magazine is the first fashion publication photographed entirely on location in high-definition, wide-screen format. Cashak Magazine photographs are comparable to Hollywood motion pictures with entertainment and fashion showcase value. The magazine compliments its fashion photography with advice and tips from industry professionals. The exclusive interviews are from fashion designers, makeup artists, hair stylists and other professionals captured in a first person, to the point perspective- not lengthy articles.

 

Mr. Cashak is a strong critic of "rerun publications" that reprint the vast majority of their content from news wires and other media outlets. He brings fashion publishing an unprecedented magazine that produces one-hundred percent of its content. The exclusive photographs and interviews found in Cashak Magazine give it a distinct advantage over publications that are dependant upon content from a shared source. Christopher Cashak simplifies this idea by saying: "If you run the same as everyone else, how will you win the race?" The magazine's content originates exclusively from professionals in the fashion industry, not amateur, student or intern contributors, which give it another unique advantage.

 

Christopher Cashak also condemns the dilution of fashion magazines with the mixing of off-topic material. In many national and local publications, which claim a fashion focus, readers will find articles on everything from real estate to sex advice, and lamp shades to celebrity gossip. Cashak Magazine intends to be a leading authority in the industry by only publishing fashion related content.

 

Single-handedly, Christopher Cashak is building Cashak Magazine without the help of a corporation or existing media outlets. He is described as a "one man publishing army" by professional peers. Through his years of experience in every aspect of publishing he is able to personally work in all parts of the magazine. Mr. Cashak simultaneously acts as the publisher, editor, photographer, interviewer, fashion stylist, photo shoot manager, web developer, public relations agent, etc. for Cashak Magazine. Mr. Cashak cites his diverse skill set as a publishing advantage: "I am able to keep a consistent vision, style and professionalism in all areas of the magazine. Rather than waiting for someone else to do it tomorrow, I can get everything done today."

 

Coming from outside the traditional fashion hubs of New York City and Los Angeles, Cashak Magazine brings a new perspective to the industry. The publication is based out of Scottsdale, Arizona- one of the major emerging fashion markets in the United States. The city is dominated by affluent and successful women who religiously search for the newest sexy styles and trends in fashion.

 

Cashak Magazine capitalizes on its local talent plus national and international fashion designers. The online preview features work of Arizona designers Susan Di Staulo, Rhonda Zayas, Tiffe Fermaint, Lisa Jacobs, Cosmopolitan Accessories, Melis Accessories, Rumbly, Inc. and more. Viewers will also find national designer Request Jeans and international jeweler Cristina Bollardi from Italy.

 

Cashak Magazine continually discovers new model, designer, makeup artist and hair stylist talent from all over the world. Prospective artists are encouraged to send a portfolio and contact information to email@cashakmagazine.com

 

Even before the official preview of Cashak Magazine went online, the publication was establishing itself as a major fashion brand. In 2005 Cashak Magazine was the sole media sponsor for the largest fashion event in Arizona, the Labelhorde Fashion Ball. The publication was also a part of the rock and roll inspired fashion event- SOUNDSTYLE. Cashak Magazine is a sponsor of the upcoming Frock n' Roll, charity fashion show and concert, held in Phoenix.

 

When asked why he took on the gargantuan task of launching a major international magazine by himself, Christopher Cashak said: "Through my years of experience I saw how not to do a magazine, now it's time for people to see how one is done right."

 

The new fashion publication, Cashak Magazine, launches an online preview at: http://www.cashakmagazine.com/

 

"Cashak" and "Cashak Magazine" are trademarks of Christopher Cashak.

 

***

 

Cashak Magazine
Scottsdale Road, Scottsdale, AZ 85251 USA
Phone: +16025249071
Email: email@cashakmagazine.com

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Mesothelioma Associated With Exposure to Volcanic Mineral

Exposure to volcanic mineral associated with increased mesothelioma incidence in Turkey

High exposure to a fibrous volcanic mineral called erionite was associated with a high incidence of a type of cancer called mesothelioma, according to a study in the March 15 issue of the Journal of the National Cancer Institute.

Public release date: 14-Mar-2006 - Many cases of environment-related mesothelioma have been reported in the Cappadocia region or Anatolian plateau of Turkey. Blocks of erionite from volcanic tuff have been used in construction, and storage rooms for produce have been cut in the tuff. Past reports have suggested that erionite exposure may increase the risk of mesothelioma, and studies have shown that erionite is associated with a higher risk of cancer development in animals than any other fiber previously tested.

Y. Izzettin Baris, M.D., of Hacettepe University in Ankara, Turkey, and colleagues followed 891 men and women age 20 years and older in three villages in Turkey – two exposed to erionite, one control – for 23 years. During this period, 372 deaths occurred, and 119 of these deaths occurred from mesothelioma. This form of cancer mainly affects the lining of the lung and was the cause of 44.5% of all deaths in the two villages with erionite exposure. Only two cases of mesothelioma occurred in the control village, both in people born outside of the control village.

The mortality data were analyzed jointly with Philippe Grandjean, M.D., Ph.D., of the Harvard School of Public Health. When standardized to the world population, the annual incidence of pleural mesothelioma in the two exposed villages was 200 and 700 cases per 100,000 people annually, compared to a rate of 10 cases per 100,000 people each year in the control village. The authors conclude that the long-term exposure to erionite is the cause of the exceedingly high risk of developing mesothelioma.

"Our results emphasize the severity of the mesothelioma endemic in erionite-exposed areas of Turkey," the authors write. They add, "In the rural part of central Anatolia, Turkey, millions of inhibitants are likely exposed to hazardous amounts of mineral fibers from the environment. Resources should therefore be directed to preventing these environmental exposures and additional study of the association between environmental exposure to nonasbestos fibers and the risk of cancer."

###

Contact: Christina Roache, Office of Communications, Harvard School of Public Health, 617-432-6052, croache@hsph.harvard.edu

Citation: Baris YI and Grandjean P. Prospective Study of Mesothelioma Mortality in Turkish Villages With Exposure to Fibrous Zeolite. J Natl Cancer Inst 2006; 98: 414-417.

Note: The Journal of the National Cancer Institute is published by Oxford University Press and is not affiliated with the National Cancer Institute. Attribution to the Journal of the National Cancer Institute is requested in all news coverage. Visit the Journal online at http://jncicancerspectrum.oxfordjournals.org/.

Contact: Ariel Whitworth
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute

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Vacuous Questions - March 17, 2006

Flip Flopper In Chief, Qué Pasó Nena?
Well, you can't have a much more girlier man than one who can't live without grabbing at women's dress hems and silently screaming: "beat me, flog me, just don't leave me!" Imagine, this Flip, Flip Flopper In Chief is encircled by Dominatrices: His cold as a witch's tit mamma, his dark as Hades and evil as Hitler Condosleezza Rice, his enabler Harriet Miers, and his dumber but butcher'n hell Karen "Polyester Pantsuit but Inane" Hughes, who is dumber than the blind salamanders so famous in her back yard. And this is the Führer 59,054,087 U.S. Sans Brains, Ethics or Patriotism twice "elected" as president? Anyway, tonight some of the gang just had some little questions about the grand plans to have Karen Hughes solve the questions of the Middle East.

 

First, Karen, Tell Us Again, Where is the Middle East?
Oh, is that the place where women are dying to wear pants like yours and drive cars? Is that their dying passion, their only dream?

With all of the events of the recent 15 days, have you been hiding your derrière where Cheney hides his when things beyond your comprehension are occurring? If not, then how come you haven't been out there in the forefront explaining "the west" to the Middle East? Oh goodness, they didn't muzzle you, did they? Heck, gal, we're paying your salary, so you are accountable to us, not only the guy whose butt you spank.

 

A Day's Labor For a Day's Pay
Hey, Karen, are you giving us our money's worth? Big title you got there gal, are we gettin' what George thinks your worth?

 

Hey gal, explain to the U.S., just what is the Euro-Mediterranean Partnership, or the Barcelona Process? Whatcha doin' to make it work? Or, do you even know what it is and when it was implemented? There's no time to play with your kid in Austin right now gal, you gotta produce, sweetie pie.

 

Well, gal, you're not as overtly repulsive or as well-recognized as the Big Mamma of Torture as 'Sleezza' Rice is, but you're close. So, if you have any redeeming virtues, explain to your country, in twelve paragraphs or less for each item, since your fellow citizens are going to be requiring it of you, what the follow subjects/headlines concern:

 

1) Israel Assaults West Bank Prison
2) Leaders Sehebaa Farms is Lebanese Territory
3) Iran, India, Pakistan Start Talks on Gas Pipeline
4) Body Counts in Iraq Keep Rising
5) Olmert Declares Ariel Settlement in West Bank Will Remain
6) Russia-Syria Arms Deal Legitimate
7) Abbas Urges EU to Continue Aid to Palestinian Government
8) Finland Pushes Dialogue on Islam
9) UN Report: Syria is Cooperating
10) Democracy May Be a Priority in the EU's Southern Policy
11) On Oil, Bush Deploys Vast Reserves of Ineptitude
12) This Is Why Islamists are Winning

 

So, Suburban-driving soccer-mom, the U.S. is holding you to account. What are the twelve-paragraph answers to these subjects? The country is waiting for your answers; if you can't answer, give up your lucrative paycheck and go back to your dumb, blind salamanders, who all look and act like your prez.

 

Dinner Gong! Sorry Karen
Enough for one night. Let's see if together we can get the Hughes gal to answer these questions to your and our satisfaction. If not, you know the next step to take up the chain of command, but for now, let's eat.

 

Charlotte prepared some Eggplant and Mozzarella on Mille Feuilles. Normally, Charlotte would make her own puff pastry, but ranching concerns forced her to use a source from which we, in a bind, get our already-prepared puff pastry, Taylor's Market, which you can access at www.taylorsmarket.com for overnight delivery of puff pastry on ice. She chose a very nice dry sparkling wine from Gruet in New Mexico. Excellent pairing, and as appetizer, it did prepare us for the dishes that were yet to come.

Marie Christine had once tried Chinese Chicken and Aspargus Soup in Paris, and attempted to replicate the recipe for us. Did she succeed? She's never failed. Her soup was glorious, and paired with an Hidalgo Pastrana Amontillado Sherry, transported us to that land we love to live in, that of the contented gourmet the people at the local feed shop love to laugh at. Food geeks indeed; just 'cause we don't chew tobacco and spit on the floor. Now really.

 

Charlotte and Beatrix put a lot of effort into their beautiful Seafood Terrine, plated with Grilled Artichokes with Lemon Oil Dip. They paired these dishes with a good Chenin Blanc from South Africa. Difficult preparation but simple plating: a wonderful treat for us.

 

Art and Max served us small dollops of Strawberry Mousse to prepare our palates for our next course, the meat course.

The bank of three Viking grills was going on the porch, and Art and Max teamed up to fix us a true delight, their Grilled Texas T-Bone Steaks, with grilled Onion Rings, Bell Peppers and Zucchini, with a side of garlicky mashed potatoes. They paired their masterpiece with an Australian shiraz, the excellent McPherson South-Eastern Australia shiraz.

 

Calming Down
Beatrix made superb Poached Pears with Crème Frâiche, one of our favorite desserts. We had ours with small snifters of Grand Marnier, thanked tonight's "chefs" and returned to the great room to spend some time with the teenagers while we sipped our after-dinner coffee Max prepared for us from his special brews. Then, we put on our jackets and headed for our respective farms and ranches, always aware of different chores still waiting because of the strange, unusual tricks the weather has been playing on us.

 

Summary
The British have officially labeled Dubya a splendiferous inept. We can only imagine what the rest of the world thinks of us, and him, and yet Dubya keeps sending equally superbly inept "envoys" out to win the hearts and minds of the Arab and Muslim worlds. We, and the Arab and Muslims, deserve better than just Bush's derrière kissers. World events are signaling events of dire importance; too much importance for the infamously xenophobic, Texas-centric Karen Hughes, or the always attitude-challenged, snide to the point of grotesqueness Condosleezza.

©Copyright 2006 Grindstaff Chronicles. All Rights Reserved.
================================================
Reprinted from The Grindstaff Chronicles Newsletter which is published in the USA by farmers, ranchers, and neighbors.

It is intended to share the thoughts and lifestyle of people who work hard, like to relax and enjoy life, and are often dismayed by news, politics, and the events of the day that defy common sense.
http://www.GrindstaffChronicles.com
================================================

Foreclosure Listings: Their Loss, Your Gain

 

HomeSaleDirectory Inc. Adds Thousands of Foreclosure Listings to Its Web Site

Partnership with Foreclosure.com to provide even more real estate opportunities for visitors.

Boca Raton, FL (PRWEB) March 15, 2006 -- Foreclosure.com today announced a partnership to provide foreclosure data to HomeSaleDirectory Inc., a rapidly growing Web-based company that brings buyers and sellers in the real estate market together.

“Real estate investors and homebuyers are constantly searching for great deals. As a result, we needed to partner with a leader in the industry that could provide us with an accurate and comprehensive selection of foreclosure listings,” said Alex Schult, president, HomeSaleDirectory, Inc. “We carefully researched the marketplace and found Foreclosure.com to be the best."

Under the agreement, HomeSaleDirectory Inc. will obtain data from Foreclosure.com and provide their site visitors with access to America’s most comprehensive database of foreclosure listings. This data includes property information and in-depth details such as exclusive tax roll information, property photos, as well as seller/listing contact information.

"Consumers are now able to search our national database of listings without ever leaving HomeSaleDirectory.com," said Zack Preble, partner relations manager, Foreclosure.com. “This partnership will remind visitors that a large inventory of foreclosed properties exists across the county. And, it will showcase the potential value that these properties often represent.”

"HomeSaleDirectory prides itself on strategic partnerships that provide our visitors with award-winning content and resources,” said Schult. “We are excited to offer the comprehensive listings that Foreclosure.com provides, and we look forward to a long and rewarding partnership.”

About HomeSaleDirectory Inc.
HomeSaleDirectory Inc. is a privately held California corporation that is quickly becoming one of the fastest growing tools on the Web, specializing in bringing buyers and sellers in the real estate market together. For more information regarding HomeSaleDirectory Inc., feel free to visit www.homesaledirectory.com or call 888-237-2507 for more information.

About Foreclosure.com
With more than 1.2 million foreclosure, preforeclosure, bankruptcy, FSBO and tax lien listings in one place, Foreclosure.com delivers America's largest and most accurate searchable database of foreclosed homes and investment property information to its customers and business partners. Based in Boca Raton, Florida, Foreclosure.com works with hundreds of top lending institutions and government agencies to list diverse property types on its Web site, including Real Estate Owned (REO); Department of Housing and Urban Development (HUD); Department of Veterans Affairs (VA); Fannie Mae; and other government agency and financial institution properties; as well as listings from an extensive network of corporate sellers. On the Web: www.foreclosure.com.

Media contact:
Thomas Myers
Foreclosure.com
(561) 981-5337 ext. 381

# # #

Press Contact: Thomas Myers
Company Name: FORECLOSURE.COM
Email: email protected from spam bots
Phone: 5619815337 . 381
Website: www.foreclosure.com

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Bush Withering

President Bush's Job Approval Ratings Continue to Drop, According to Latest Harris Poll

 

Less than one-third of U.S. adults believe the country is going in the right direction

 

ROCHESTER, N.Y., March 14 /PRNewswire/ -- Although slightly better than the lowest approval ratings measured during his presidency (34% positive, 65% negative in November 2005), President Bush's job approval numbers have again taken a downward slide this month as just over one-third (36%) of U.S. adults rate his job performance as positive and 64 percent rate his performance as negative. In February, 40 percent viewed the president's job performance positively while 58 percent viewed it negatively. Some of this may be linked to the thoughts on the state of the country as 31 percent believe the country is moving in the right direction while 60 percent feel things have pretty seriously gotten off on the wrong track. This is directionally down from last month when 32 percent felt the country was moving in the right direction and 59 percent felt things had pretty seriously gotten off on the wrong track.

 

These are some of the results from the latest Harris Poll of 1,001 U.S. adults surveyed by telephone between March 3 and 7, 2006 by Harris Interactive(R).

 

For the first time, The Harris Poll(R) measured the job performance ratings for Supreme Court Chief Justice John Roberts. The chief justice starts off his tenure on the Court with 41 percent of U.S. adults viewing his job performance positively and 36 percent viewing it negatively. It will be interesting to see if the percentage of adults who say they are "not sure" about this job performance (23%) stays this high as the nomination and subsequent media coverage fades from the public's memory.

 

Administration ratings

 

For the first time since the hunting accident, Vice President Dick Cheney's job approval ratings were measured. Three in 10 U.S. adults view his job performance positively while 67 percent view it negatively. What is interesting is that there is no real change from November, prior to the accident, when 30 percent had a positive view and 65 percent had a negative view.

 

For two other administration officials, the news is mixed. Secretary of State Condoleezza Rice still receives the highest performance ratings among all political figures measured in the poll as 51 percent have a positive view of her job performance as compared to 44 percent who have a negative view. While Secretary Rice's positive approval rating remained similar to what was measured in November 2005 (52%), her negative rating increased three percentage points (from 41%). Similarly for Secretary of Defense Donald Rumsfeld, his positive rating has remained steady (34% in November to 35% now), while his negative rating has increased slightly (59% in November to 61% now).

 

This month we also asked about Deputy Chief of Staff Karl Rove. Just over one-quarter (28%) rate the job he is doing positively while over half (55%) rate it negatively. U.S. adults appear more likely to have an opinion about Karl Rove, one way or another, than all four of the members of Congress and the Supreme Court Chief Justice included in this poll, as indicated by the percentage of "not sure's."

 

Congressional ratings

 

Republicans and Democrats in Congress can take some solace in the fact that their numbers have not changed much from November. However since they were not that good in November, this may not necessarily be good news for them. This month, Republicans have a 27 percent positive job approval rating while 68 percent of U.S. adults view their performance as negative. Democrats fair slightly worse with a 24 percent positive job approval rating and a 70 percent negative rating. In November, Republicans were 27 percent positive, 69 percent negative while Democrats were 25 percent positive, 70 percent negative.

 

Much of this negativity toward the two parties in Congress is also seen in the job performance numbers of some of its leaders.

 

  * Republican Senate Majority Leader Bill Frist has a 21 percent positive
    approval rating and a 55 percent negative rating. This is down from
    November when he had a positive rating of 23 percent and a negative
    rating of 52 percent.
  * Things aren't much better for Democratic Senate Minority Leader Harry
    Reid as about one in five adults (19%) gives him a positive job approval
    rating while over half (53%) view his job performance negatively. When
    his performance was last measured in August, about one-quarter (24%)
    viewed his job performance positively while 47 percent viewed it
    negatively.
  * In the House, Republican Speaker Dennis Hastert has seen a slight up
    tick in his approval ratings. This month they are at 26 percent
    positive, up from 22 percent in November, while his negative job rating
    is at 49 percent, down from 50 percent.
  * Also measured for the first time was new Republican House Majority
    Leader John Boehner who starts with a job approval of 23 percent
    positive and 50 percent negative.

 

Important issues

 

Again this month, the most important issue for the government to address according to the American public is the war in Iraq, but that number has taken a dip. This month, 21 percent of U.S. adults believe it is the most important issue to address as compared to last month when 27 percent felt this way. Healthcare is next as 16 percent of adults believe the government should address this issue, closely followed by the economy (15%). While fewer adults think the war and healthcare are the most important issues (down 6 percentage points and 4 percentage points, respectively, from last month), more adults think gas and oil prices (up from 2% to 5%) and employment issues (up from 5% to 8%) should be top priorities.

 

TABLE 1

 

CURRENT RATINGS OF PRESIDENT, SENIOR CABINET MEMBERS AND PARTIES IN CONGRESS "How would you rate the job (READ ITEM) are/is doing - excellent, pretty good,

 

                           only fair, or poor?"

 

  Base: All Adults

 

                    Excellent  Pretty  Only   Poor  Not Positive* Negative**
                                Good   Fair         Sure
  Secretary of
   State Condoleezza
   Rice              %   19      32     29     16    5     51        44
  President George
   W. Bush           %    9      27     22     41   ***    36        64
  Secretary of
   Defense Donald
   Rumsfeld          %    8      28     29     31    4     35        61
  Vice President
   Dick Cheney       %    7      23     26     41    3     30        67
  Chief Justice
   John Roberts      %    8      33     29     8    23     41        36
  Deputy White House
   Chief of Staff
   Karl Rove         %    5      23     33     23   17     28        55
  Democrats in
   Congress          %    3      21     43     27    6     24        70
  Republicans in
   Congress          %    3      24     35     33    6     27        68
  Senate Minority
   Leader Harry Reid %    1      17     36     17   28     19        53
  Senate Majority
   Leader Bill Frist %    2      19     38     17   24     21        55
  House Speaker
   Dennis Hastert    %    3      24     36     14   24     26        49
  House Majority
   Leader John
   Boehner           %    2      21     38     11   28     23        50

 

  *Positive = excellent or pretty good.
  **Negative = only fair or poor
  ***Less than 0.5%.

 

                                 TABLE 2
             POSITIVE RATINGS: TRENDS SINCE 9/11/01: SUMMARY

 

  Base: All Adults

 

   POSITIVE RATINGS    Soon
                       After   Feb.  April   Aug.  Dec.  Feb.  April  June
                       9/11    2003   2003   2003  2003  2004  2004   2004
  President George
   W. Bush          %   88      52     70     57     50   51    48    50
  Vice President
   Dick Cheney      %   69      45     55     42     42   41    36    42
  Secretary of
   State Condoleezza
   Rice             %   **      **     **     **     **   **    **    **
  Secretary of
   Defense Donald
   Rumsfeld         %   78      56     71     55     57   50    45    47

 

  POSITIVE RATINGS         Nov.   Feb.  April   June    Aug.  Nov.   Mar.
                           2004   2005   2005   2005   2005   2005   2006
  President George
   W. Bush            %     50     48      44    45      40    34      36
  Vice President
   Dick Cheney        %     48     45      37    38      35    30      30
  Secretary of State
   Condoleezza Rice   %     **     52      54    52      57    52      51
  Secretary of
   Defense Donald
   Rumsfeld           %     47     42      42    42      40     34     35

 

  ** N/A

 

                                 TABLE 3
                   PRESIDENT BUSH'S OVERALL JOB RATING
                          (Not Sure's Excluded)

 

 "How would you rate the overall job President George W. Bush is doing as
         president - excellent, pretty good, only fair, or poor?"

 

  Base: All Adults

 

                           TREND                    Positive*    Negative**
  2006                     March            %           36           64
                           February         %           40           58
                           January          %           43           56
  2005                     November         %           34           65
                           August           %           40           58
                           June             %           45           55
                           April            %           44           56
                           February         %           48           51
  2004                     November         %           50           49
                           October          %           51           49
                           September        %           45           54
                           August           %           48           51
                           June             %           50           49
                           April            %           48           51
                           February         %           51           48
  2003                     December         %           50           49
                           October          %           59           40
                           August           %           57           41
                           June             %           61           36
                           April            %           70           29
                           February         %           52           46
  2002                     December         %           64           35
                           November